Sample Report - This is an example of what your personalized DNA insights report looks like. The data shown is from a real (anonymized) analysis.

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Your DNA Insights Report

Prepared for Sample

Generated December 12, 2025

How to read this report

This report summarizes genetic tendencies related to thyroid function, immune regulation, hormone metabolism, and stress response.

Genetics reflects patterns, not diagnoses. A tendency shows what your DNA may influence — not what will happen.

Each section explains what your results may mean and — equally important — what they do not mean.

Understanding tendency levels

Low

Typical genetic pattern — no specific concerns suggested

Moderate

Common pattern — may be worth awareness

Higher

Pattern associated with increased attention — but not a diagnosis

Hover over any badge throughout this report for more context.

Data Coverage

93%

Excellent coverage — your file contained most of the markers we analyze.

Coverage reflects how many relevant markers were found in your uploaded file. Lower coverage means fewer data points — not higher or lower risk.

Your Results at a Glance

This report is saved securely. You can return anytime using your email.

Thyroid Function & Conversion

Moderate Tendency
70% coverage (7/10 markers)

What this means

Your genetic profile shows some common variations in genes involved in how the body processes thyroid hormones, particularly the conversion of T4 (the storage hormone) into T3 (the active hormone). A moderate tendency like this is very common and does not, on its own, indicate a thyroid disorder. It simply means that, compared to population averages, your body may process thyroid hormones a bit differently under certain conditions.


Why this matters

Thyroid hormones play a role in many aspects of how your body functions. Most thyroid hormone is produced as T4, which then needs to be converted into T3 inside tissues. Genetic differences in conversion pathways can influence how efficiently this process happens, but they do not determine how your thyroid is functioning today.

  • energy levels
  • temperature regulation
  • metabolism
  • brain function

Many people with similar genetic patterns have:

  • normal thyroid labs
  • no symptoms
  • no need for treatment

Understanding the pathway

This diagram illustrates how thyroid hormone is produced and converted in the body, highlighting the step where T4 is converted into the active hormone T3.

For you: Your result suggests that some of the genes involved in this conversion step differ slightly from the population average. This does not mean conversion is impaired, only that this pathway may be more sensitive to factors like illness, stress, nutrient status, or hormonal changes.

Thyroid Hormone Conversion Pathway

TSHThyroidT4DIO2T3(active)
Understanding This Diagram
Low Tendency

Typical genetic variants

Moderate TendencyYour result

Some variation present

Higher Tendency

Multiple variants identified

dashed

Note: These results reflect genetic tendencies only, not a diagnosis. Many factors including lifestyle, environment, and other genes influence actual health outcomes. Your healthcare provider can help interpret these results in context.

This diagram highlights the biological pathway influenced by the genetic variants reviewed in this section.


What this may mean

  • You may have genetic variants that influence how efficiently T4 converts to T3.
  • In some people, this pattern is associated with symptoms only when combined with other factors (such as stress, inflammation, or hormonal shifts).
  • Genetics may help explain why some people feel symptoms even when basic thyroid labs look normal — but it does not explain this on its own.

What this does NOT mean

  • This does not diagnose hypothyroidism or any thyroid condition.
  • This does not mean your thyroid is underactive or "not working."
  • This does not predict whether you will develop thyroid disease.

How common is this?

A moderate conversion tendency is very common in the general population. Many clinicians see similar genetic patterns routinely, especially in women, and most people with these variants never require medical intervention. Genetics represents just one layer of thyroid health.


When to explore further

If you're already monitoring or have relevant symptoms, these are the labs commonly used to evaluate this area. No immediate action is typically needed for moderate patterns.

If you have symptoms or a known thyroid condition, a comprehensive thyroid panel (TSH, Free T4, Free T3) can help assess how your thyroid is functioning right now. Labs provide real-time information that genetics cannot.

Key takeaway

Your genetics suggest a common, moderate variation in thyroid hormone processing. This information can be useful context, but it does not define your thyroid health. Symptoms, labs, and clinical evaluation are far more important than DNA alone.

Hashimoto's & Autoimmune Tendency

Low Tendency
100% coverage (10/10 markers)

What this means

Your genetic profile shows typical variations in immune-related genes. This common pattern does not suggest any increased tendency for autoimmune thyroid conditions.


Why this matters

The immune system protects your body from illness, but sometimes it can affect healthy tissues, including the thyroid. Understanding your genetic patterns in immune regulation can help you have informed conversations with your healthcare provider.

  • immune system balance
  • thyroid protection
  • inflammation response
  • overall wellness

Many people with similar genetic patterns have:

  • no autoimmune conditions
  • normal thyroid antibodies
  • healthy immune function

Understanding the pathway

This diagram shows how the immune system interacts with the thyroid gland and the factors that influence immune balance.

For you: Your genetic pattern suggests typical immune regulation. The pathways shown in this diagram function normally in most people with your profile.

Immune Regulation Pathway

T-Cell(immune)CheckpointCTLA4/PTPN22Thyroid(target)Genetic variants may influence immune self-tolerance
Understanding This Diagram
Low TendencyYour result

Typical genetic variants

Moderate Tendency

Some variation present

Higher Tendency

Multiple variants identified

dashed

Note: These results reflect genetic tendencies only, not a diagnosis. Many factors including lifestyle, environment, and other genes influence actual health outcomes. Your healthcare provider can help interpret these results in context.

This diagram highlights the biological pathway influenced by the genetic variants reviewed in this section.


What this may mean

  • Your genetic profile shows typical immune regulation variants.
  • This pattern does not indicate increased autoimmune tendency.
  • Lifestyle and environmental factors also influence immune health.

What this does NOT mean

  • This does not mean you have Hashimoto's or any autoimmune condition.
  • Many people with these variants never develop autoimmune thyroid issues.
  • Only antibody testing can assess current autoimmune thyroid activity.

How common is this?

A low autoimmune tendency is very common and represents typical genetic variation in immune-related genes.


When to explore further

Based on your low tendency pattern, routine monitoring is usually sufficient. Discuss with your provider if symptoms develop.

Key takeaway

Your genetics show typical immune regulation patterns. Your current symptoms and lab results are what matter most for understanding your immune and thyroid health.

Menopause & Hormone Sensitivity

Low Tendency
100% coverage (10/10 markers)

What this means

Your genetic profile shows typical variations in hormone-related genes. This common pattern does not suggest any particular tendency for hormone-related symptoms.


Why this matters

Hormones influence energy, mood, sleep, and many aspects of wellbeing. Understanding your genetic patterns can help you prepare for and navigate hormonal transitions, though genetics is just one of many factors involved.

  • energy and mood
  • sleep quality
  • bone health
  • cognitive function

Many people with similar genetic patterns have:

  • smooth hormonal transitions
  • minimal menopause symptoms
  • stable mood and energy

What this may mean

  • Your genetic profile shows typical hormone receptor and metabolism variants.
  • Hormone experiences vary widely regardless of genetic patterns.
  • Many factors influence how you experience hormonal changes.

What this does NOT mean

  • This does not predict when or how you will experience menopause.
  • Genetic patterns do not determine symptom severity.
  • Hormone levels can only be assessed through blood testing.

How common is this?

A low hormone sensitivity tendency is common and represents typical genetic variation. Most women have some variation in these genes.


When to explore further

Based on your low tendency pattern, routine monitoring is usually sufficient. Discuss with your provider if symptoms develop.

Key takeaway

Your genetics show typical patterns in hormone-related genes. Your symptoms and hormone levels are what matter most for understanding your hormonal health.

Metabolism & Stress Response

Low Tendency
100% coverage (10/10 markers)

What this means

Your genetic profile shows typical variations in metabolism and stress response genes. This common pattern does not suggest any particular metabolic tendency.


Why this matters

Metabolism and stress response affect energy, weight management, and overall wellbeing. Understanding these patterns can help you make informed lifestyle choices, though genetics is just one piece of the puzzle.

  • energy production
  • weight management
  • blood sugar balance
  • stress resilience

Many people with similar genetic patterns have:

  • healthy metabolic function
  • stable energy levels
  • normal glucose metabolism

Understanding the pathway

This diagram shows the pathways of energy metabolism and stress hormone response, including how glucose is processed and how the body responds to stress.

For you: Your genetic pattern suggests typical metabolic function. The pathways shown operate similarly in most people with your profile.

Metabolism & Stress Response

Glucose MetabolismGlucoseTCF7L2signalingCelluptakeStress ResponseHPAaxisCRHCRHR1Cortisolresponseinterplay
Understanding This Diagram
Low TendencyYour result

Typical genetic variants

Moderate Tendency

Some variation present

Higher Tendency

Multiple variants identified

dashed

Note: These results reflect genetic tendencies only, not a diagnosis. Many factors including lifestyle, environment, and other genes influence actual health outcomes. Your healthcare provider can help interpret these results in context.

This diagram highlights the biological pathway influenced by the genetic variants reviewed in this section.


What this may mean

  • Your genetic profile shows typical metabolic pathway variants.
  • Metabolism is highly influenced by diet, exercise, and lifestyle.
  • This pattern does not indicate metabolic concerns.

What this does NOT mean

  • This does not diagnose diabetes, insulin resistance, or metabolic conditions.
  • Genetic tendency is not destiny—lifestyle has enormous impact.
  • Only lab tests can assess your current metabolic status.

How common is this?

A low metabolic tendency is common and represents typical genetic variation. Most people have some variation in these genes.


When to explore further

Based on your low tendency pattern, routine monitoring is usually sufficient. Discuss with your provider if symptoms develop.

Key takeaway

Your genetics show typical patterns in metabolic genes. Your lifestyle choices and current lab values are what matter most for metabolic health.

What Genetics Can — and Cannot — Explain

Understanding the role of DNA in your health

What genetics CAN show

  • Genetic tendencies based on research associations
  • Potential areas worth awareness
  • A starting point for informed conversations with your provider
  • Which lab tests might be most relevant for you

What genetics CANNOT show

  • A diagnosis of any medical condition
  • Your current hormone or thyroid levels
  • Whether you will develop any specific condition
  • How you should be treated medically

The bottom line: Your symptoms and lab results matter more than your genetics. DNA shows possibilities — lab tests show your actual health today.

Questions about your results? We recommend discussing them with a healthcare provider who can review your complete health picture.

Important Information

Important Disclaimer

This report provides educational insights based on published genetic research. It is NOT: - A medical diagnosis - A substitute for lab testing - Medical advice or treatment recommendations

Genetic tendencies are just one factor in health. Many people with "higher tendency" markers never develop related conditions, while others without these markers may.

Always discuss your health concerns with a qualified healthcare provider. If you're experiencing symptoms, please seek appropriate medical evaluation.

The information presented is based on current scientific understanding and may be updated as research evolves.

Ready to discover your own insights?

Upload your DNA file from 23andMe, AncestryDNA, or other providers to get your personalized thyroid and hormone insights.